FRACTURE HEALING
Like healing of soft tissue wounds, healing of fracture is very similar, except the end result is mineralised mesenchymal tissue ( bone).
Healing of a fracure begins as soon as it is broken through a continous stages of healing.
Stages of fracure healing of cortical bone (FROST, 1989)
1. Stage of haematoma
2. Stage of granulation tissue
3. Stage of callus
4. Stage of remodelling
5. Stage of modelling
Stage of haematoma:
last upto 7 daysfracture end necrosis occurssensitisation of precurser cellsStage of granulation tissue:
upto 2-3 weeksproliferation and differentiation of daughter cells into vessels, fibroblasts, osteoblasts etcfracture still mobile Stage of callus:
last upto 4-12 weeksmineralisation of granulation tissueradiologically visible calusStage of remodelling:
lasts upto 2 yearslamellar bone formation remodelling of calluscallus becomes sharply defined and densedStage of modelling
lasts many yearsendosteal and periosteal modelling …
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